含氟贫电子环丙烷衍生物的简便合成  

Convenient Synthesis of Electron-deficient Cyclopropane Derivatives Containing Fluorine

作　　者：施志坚[1] 刘梅[1] 梁超[1] 

机构地区：[1]上海大学化学系

出　　处：《合成化学》2008年第5期546-549,共4页Chinese Journal of Synthetic Chemistry

基　　金：国家自然科学基金资助项目(20472047)

摘　　要：从含氟取代基的芳醛从发,制备一系列贫电子烯烃(3);3与鉮盐反应,高立体选择性地合成了含氟贫电子环丙烷衍生物,其结构经1H NMR,13C NMR,IR,MS和元素分析表征,立体构型由二维NOE实验确定。A series of electron-deficient olefins（3） containing fluorine were prepared from aromatic aldehydes containing fluorine. 3 reacted with arsenic salts to give the electron-deficient cyclopropanes containing fluorine with high stereoselectivity. The structures were characterized by ^1H NMR, ^13C NMR, IR, MS and elemental analysis. The spatial configurations were identified by NOESY.

关 键 词：芳醛 氟 贫电子化合物 环丙烷衍生物 立体选择性合成 

分 类 号：O624.1[理学—有机化学]