固体碱K_2CO_3/Al_2O_3催化酯交换法合成乙二醇甲醚乙酸酯  

Synthesis of 2-Methoxyethyl Acetate by Transesterification on the Solid Base K_2CO_3/Al_2O_3

作　　者：龚国珍[1] 梁学正[1] 王箭[1] 权南南[1] 张敬[1] 鲍少华[1] 杨建国[1] 

机构地区：[1]华东师范大学上海市绿色化学与化工过程绿色化重点实验室,上海200062

出　　处：《精细化工》2008年第10期982-984,998,共4页Fine Chemicals

基　　金：国家支撑计划项目(2006BAE03B06);上海市重点学科建设项目(B409);上海市科委资助的国际科技合作项目(06SR07101)~~

摘　　要：以固体碱K2CO3/Al2O3为催化剂,催化乙酸乙酯和乙二醇甲醚酯交换合成了乙二醇甲醚乙酸酯。考察了反应物摩尔比,催化剂用量,反应时间,催化剂重复使用等因素对反应的影响,结果表明:当n(乙酸乙酯)∶n(乙二醇甲醚)=4∶1,K2CO3/Al2O3用量为总反应物质量的1.0%,反应4.5h时,乙二醇甲醚的转化率为98.8%,选择性为100%;催化剂重复使用5次后,乙二醇甲醚的转化率仅下降3.7%。2-Methoxyethyl acetate was synthesized using ethyl acetate and ethylene glycol monomethyl ether as reactants and the solid base K2CO3/Al2O3 as catalyst. Effects of molar ratio of reactants, catalyst dosage ,reaction time and catalyst reuse were discussed. With 1% K2CO3/Al2O3 and n （ethyl acetate）/n（ ethylene glycol monomethyl ether） = 4, reacting at 80 - 110 ℃ for 4. 5 h, conversion of ethylene glycol monomethyl ether was 98.8%. In addition, K2CO3/Al2O3 could be recovered after 5 times reuse without significant loss of its catalytic activity.

关 键 词：K2CO3/Al2O3 酯交换反应 乙二醇甲醚乙酸酯 

分 类 号：TQ225.241[化学工程—有机化工] TQ032.41