Maroni公式评估慢性肾脏病患者饮食蛋白质摄入在国人中的应用  

Validating the Maroni’s Formula of estimating protein intake of Chinese patients with chronic kidney disease

作　　者：李素蘋[1,2] 许菲菲[3] 

机构地区：[1]温州医学院,在职研究生325000 [2]温州市第二人民医院肾内科 [3]温州医学院附属第一医院肾内科,325000

出　　处：《浙江临床医学》2008年第10期1310-1312,共3页Zhejiang Clinical Medical Journal

摘　　要：目的了解Maroni公式是否能准确反映我国慢性肾脏病(CKD)患者的每日蛋白质摄入(eDPI)情况。方法选择2006年11月至2007年4月住院的各期CKD患者100例,根据24h尿蛋白排泄量分为A、B、C三组,营养膳食科根据其标准体重、原发病及肾功能分级制订相应的饮食方案,3d后收集其24h尿液标本测定24h尿尿素氮量(UUN),根据Maroni公式,利用24hUUN来估算患者eDPI,并与患者留取尿液标本当日实际营养处方的DPI配对,以验证两者符合率。结果三组CKD患者应用Maroni公式估算的eDPI与其当日实际营养处方的DPI相比,P均>0.05,无显著性差异。结论本研究结果提示24h尿蛋白排泄量不影响应用Maroni公式估算的我国CKD患者eDPI。通过该公式估算的我国各期CKD患者的eDPI与实际营养处方的DPI一致。因此,Maroni公式是适用评估我国CKD患者饮食蛋白质摄入的一种简便、准确的方法。Objective To validate the Maroni＇ s Formula of estimating protein intake of Chinese patients with chronic kidney disease. Methods From November 2006 to April 2007, 100 eases of the CKD patients were assigned to 3 groups according to their 24 hours urine protein excretion amount： A group, 24 hours urine protein excretion amount 〉 3.0g/24h ; B group, 〈 3.0g/24h but 〉 1.0g/24h ; and C group, 〈 1.0g/24h . They were given appropriate diet based on their GFR , and their 24 hours UUN were detected 3 days after to estimate their protein intake by the Maroni＇ s Formula , then their eDPI were compared with their prescribed DPI on the same day. Results The eDPIs of A, B, C groups and their prescribed DPIs respectively did not differ statistically by paired analysis（ P 〉 0.1 ） as well as those in the total population of the 100 patients. Conclusion This study suggests that the Maroni＇ s formula of estimating protein intake is valid to Chinese patients with chronic kidney disease as same as it do to the patients of Occidental country , and there was no difference among the three subgroups.

关 键 词：慢性肾脏病 每日蛋白质摄入 Maroni公式 

分 类 号：R692[医药卫生—泌尿科学]