半枝莲的化学成分研究(Ⅱ)  

Chemical constituents of Scutellaria barbata D.Don(Ⅱ)

作　　者：李萍[1] 左甜甜 王晓秋[1] 朱邻遐[1] 伍实花[1] 张国刚[1] 

机构地区：[1]沈阳药科大学中药学院,辽宁沈阳110016

出　　处：《中国药物化学杂志》2008年第5期374-376,共3页Chinese Journal of Medicinal Chemistry

摘　　要：目的研究半枝莲的化学成分。方法利用多种分离方法,从半枝莲全草的乙醇提取液中分离得到7个化合物,利用理化性质和波谱学分析,鉴定它们的化学结构。结果分离鉴定了7个已知化合物,分别是对羟基苯甲醛(1)、反式-1-(4′-羟基苯基)-丁-1-烯-3-酮(2)、对羟基苯甲酸乙酯(3)、对羟基苯乙酮(4)、松脂素(5)、杜仲树脂酚(6)、豆甾醇(7)。结论化合物5、6为首次从该属植物中分得的已知化合物。Aim To investigate the chemical constituents of Scutellaria barbata D. Don. Methods Seven compounds were separated from the whole plant and their structures were identified by the spectral analysis and chemical evidence. Results Seven compounds were isolated and identified as p-hydroxybenzaldehyde（1）, E- 1-（4＇-hydroxyphenyl ）-but-l-en-3-one （ 2 ）, ethyl 4-hydroxybenzoate （ 3 ）, p-hydroxyacetophenone （ 4 ）, pinoresinol（5）, medioresinol （6）, and stigmasterol （7）. Conclusion Compounds 5 and 6 were isolated from Scutellaria for the first time.

关 键 词：结构鉴定 柱色谱 波谱分析 半枝莲 乙醇提取物 

分 类 号：R284.1[医药卫生—中药学]