大面积烧伤患者外周血T淋巴细胞亚群的研究  

Study on T Lymphocyte Subsets of Large Area Burn Patients

作　　者：许坤[1] 张利[1] 张静然[1] 

机构地区：[1]解放军第251医院,河北张家口075000

出　　处：《实用医技杂志》2008年第21期2745-2746,共2页Journal of Practical Medical Techniques

摘　　要：目的:探讨大面积烧伤患者T淋巴细胞亚群变化及其临床意义。方法:采用直接免疫荧光法,应用流式细胞仪,检测45例烧伤患者及15例健康人外周血CD3+T细胞、CD4+T细胞、CD8+T细胞的数值及CD4+/CD8+比值。结果:与正常对照组比较,CD4+细胞数明显降低(P<0.05);CD4+/CD8+比值明显降低(P<0.05)。结论:烧伤患者外周血中的T淋巴细胞亚群在发病机制中起重要作用。Objective Large area of burns patients T lymphocyte subsets change and its clinical significance. Methods Using direct immun of luoreseence, the value of CD3 ＋ T cells,CD4＋ T cells,CD8＋ T cells and CD4 ＋/CD8＋ in 45 eases of burn patients and 15 healthy people＇s Peripheral blood were detected by FCM. Results With the normal control group, CD4＋ cells decreased significantly （ P 〈 0.05 ） ; CD4 ＋/CD8＋ ratio decreased significantly（ P 〈0. 05 ）. Conclusion Burn patients with the T lymphocyte subsets in the pathogenesis of play an important role.

关 键 词：烧伤患者 T淋巴细胞亚群 流式细胞技术 

分 类 号：R644[医药卫生—外科学]