冠心病合并代谢综合征患者踝臂指数与冠脉病变程度的关系  

Relationship between abnormal ankle brachial index and extent of coronary artery stenosis in aged coronary artery disease patients with metabolism syndrome

作　　者：逯春鹏[1,2] 胡大一[3,4,2] 杨进刚[2] 王昆[5] 刘云宝 陈秋萍 

机构地区：[1]清华大学第一附属医院,北京100016 [2]首都医科大学附属北京同仁医院心血管疾病诊疗中心 [3]同济大学医学院 [4]北京大学人民医院心脏中心 [5]清华大学第二附属医院

出　　处：《心血管康复医学杂志》2008年第5期479-481,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:研究合并代谢综合征(MS)冠心病患者MS与踝臂指数和冠脉病变的严重程度的关系。方法:连续入选经冠状动脉造影明确诊断为冠心病的老年患者,评估冠脉病变情况,测定其踝臂指数(ABI),根据是否存在MS及ABI正常与否进行分组,分析单独及联合MS、ABI≤0.90预测冠心病冠脉病变程度的状况。结果:共入选151例冠心病患者,其中合并MS者64例,无MS者87例。相对于无MS组,MS组的低ABI(≤0.9)比例明显增高(43.8%∶27.6%,P=0.039);ABI值更低(0.91±0.31)∶(1.02±0.25),P=0.016;低ABI者三支病变显著增多(60.9%∶32.2%,P=0.000),而单支病变明显较少(18.8%∶42.5%,P=0.002)。结论:冠心病患者如合并代谢综合征,则ABI值更低,冠状动脉病变更加严重,应进行强化治疗。Objective： To study the relationship between abnormal ankle brachial index （ABI） and extent of coronary artery stenosis in aged coronary artery disease patients with metabolism syndrome. Methods： A total of 151 patients with coronary artery disease were study subjects. In which, 64 cases complicated MS, 87 cases without MS. ABI was examined in all patients. Results： Compared with non MS group, a significant lower ratio of ABI （43.8% ： 27.6%, P=0.039）, lower ABI [ （0.91±0.31） ： （1.02±0.25）, P=0.016] in MS group; whereas much more 3-- vessel disease （60.9%： 32.2%, P=0. 000）, a fewer single-vessel disease in ABI≤0.90 group compared with those of ABI normal group （18.8% ： 42.5%, P=0. 002）. Conclusion： There is more severe of coronary artery stenosis in ABI≤ 0.90 patients for CAD patients with metabolic syndrome, should pay more attention to CAD patients combined with MS and ABI≤0.90.

关 键 词：冠状动脉疾病 代谢综合征 诊断 

分 类 号：R541.75[医药卫生—心血管疾病]