运动与骨肽制剂对骨质疏松骨密度影响的临床观察  

Influence of Exercise and Ossotide Injection to Osteoporosis

作　　者：李鸿波[1] 梅强[1] 阴小龙[1] 常瑞[1] 

机构地区：[1]陕西中医学院,陕西西安710077

出　　处：《河南职工医学院学报》2008年第5期446-447,共2页Journal of Henan Medical College For Staff and Workers

摘　　要：目的观察骨肽加运动疗法对绝经后骨质疏松症患者腰椎骨骨密度的改善作用。方法符合纳入标准的70例患者随机分为运动组38例，对照组32例。对照组仅用骨肽治疗，运动组用骨肽并做有计划的运动。观察两组治疗前后L1～4椎体骨密度变化情况。结果运动组治疗前骨密度为0．48±0.32g·cm^-2，对照组为0．46±0．25g·cm^-2，两组比较差异无显著性意义（P〉0．05）。治疗6个月后运动组骨密度为0．53±0．19g·cm^-2；对照组为0．48±0．22g·cm^-2。运动组腰椎骨密度明显高于对照组（P〈0．05）。结论运动疗法加骨肽对绝经后骨质疏松症腰椎骨密度有明显的改善作用。Objective To observe the improving effects of Ossotide injection combined with exercise therapy on lumbar spinal bone mineral density in postmenopausal osteoporosis patients. Methods 70 postmenopausal osteoporosis patients were randomly divided into exercise group （ n = 38） and control group （n = 32）. The control group was treated with Ossotide injection only, and the exercise group was treated with Osstide injection combined with planned exercise. The lumbar spinal bone mineral density of the two groups were all examined. Results The lumbar spinal bone density of the two groups before therapy was 0.48 ±0.32 g·cm^-2 and 0.46 ±0.25 g·cm^-2 respectively. There were no significant differences between them （P 〉 0.05 ）. After 6 months, exercise, the lumbar spinal bone density of exercise group （0.53±0. 19g·cm^-2） was higher than that of control group （0.48 ±0.28g·cm^-2） （P 〈 0.05）. Conclusion Ossotide injection combined with exercise has obvious improving effects on bone mineral density in postmenopausal osteoporosis patients

关 键 词：骨质疏松症 骨肽注射液 运动 骨密度 

分 类 号：R681[医药卫生—骨科学]