支气管哮喘病人三维正脊治疗前后血清TNF-α、GM-CSF测定的临床意义  

The Clinical Effects of the Level of TNF-A and GM-CSF of Bronchial Asthma Patients Treated with Three-dimensional Rectification Apparatus

作　　者：刘军[1] 项良碧[1] 陈语[1] 韩文峰[1] 曹燕[1] 李军[1] 

机构地区：[1]沈阳军区总医院骨科,沈阳110015

出　　处：《中国医药导刊》2008年第6期895-895,901,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨支气管哮喘病人三维正脊治疗前后血清肿瘤坏死因子-α(TNF-α)、粒细胞-巨噬细胞集落刺激因子(GM-CSF)水平测定的临床意义。方法:选取支气管哮喘患者60名,按入院时间随机分为正脊组、模型组(各30名),另选取30名健康成人作对照组。分别于患者入院后及正脊治疗后10天应用放射免疫分析方法测定血清TNF-α、GM-CSF含量。结果:治疗前支气管哮喘病人血清TNF-α、GM-CSF水平显著高于正常组(p<0.01),经三维正脊仪治疗10d后二者水平与正常人比较则无显著性差异(p>0.05)。结论:三维正脊治疗对支气管哮喘病人具有积极的治疗作用,检测支气管哮喘患者血清TNF-α、GM-CSF水平的变化对了解病情及预后观察具有一定的临床价值。Objective： To investigate the clinical effects of the level of TNF-Aand GM-CSF in serum for bronchial asthma patients before and after the treatment with three-dimensional rectification apparatus. Method： Sixty patients of bronchial asthma were selected and randomized into two groups. Thirty heahhy adults were selected as control group. The level of TNF-A and GM-CSF in serum of them before or after being treated with three-dimensional rectification apparatus was determined. Results： the level of TNF-A and GM- CSF of patients without treatment was significantly higher than that of healthy volunteers （p〈0.01）. While the patients who were treated with three-dimensional rectification apparatus, had similar level of TNF-Aand GM-CSF with those healthy volunteers. Conclusions：It showed that three-dimensional rectification apparatus has active effects on the patients of bronchial asthma. The level of TNF-Aand GM-CSF has certain chnical effects for Clinical observation of patients＇condition and prognosis.

关 键 词：支气管哮喘 正脊疗法 肿瘤坏死因子-α(TNF-α) 粒细胞-巨噬细胞集落刺激因子(GM—CSF) 

分 类 号：R244.1[医药卫生—针灸推拿学] R562.25[医药卫生—中医临床基础]