腹泻患儿轮状病毒感染致肝脏损害临床分析  

Clinical analysis of liver lesion with rotavirus diarrhea infants

作　　者：戴颖[1] 何书[1] 汪奇伟[1] 

机构地区：[1]河南大学淮河医院儿科,开封475000

出　　处：《临床医学》2008年第9期35-36,共2页Clinical Medicine

摘　　要：目的研究婴幼儿轮状病毒肠炎与肝脏损害的关系。方法对106例腹泻患儿用金标法检测大便轮状病毒抗原,检测其肝功能,按照大便轮状病毒抗原检测结果分为观察组(大便轮状病毒抗原阳性组)和对照组(大便轮状病毒抗原阴性组),对其结果进行对比分析。结果观察组与对照组肝功能异常发生率比较差异有统计学意义(P<0.01);肝功能异常发生率与患儿发病年龄比较差异有统计学意义(P<0.01);丙氨酸氨基转移酶升高与临床脱水程度比较差异无统计学意义(P>0.05)。结论婴幼儿轮状病毒肠炎常合并肝脏损害,所致的肝脏损害程度与患儿脱水的严重程度无明显相关性,年龄越小肝功能异常发生率越高。Objective To investigate the relation rotavirus infection to liver lesion indrarrhea infants. Methods One hundred and six cases suffering diarrhea into rotavirus antigen positive group （observations group） and rotavirus antigen negative group （controls group ）, using rapid diagnostic test rotavirus antigen at the same time, drawing blood to measure liver function. Results The observations group had significant difference with controls group in the occurrence of the abnormal function of liver. The rate of unfuction of liver had obvious difference with the age of infant patients. The higher level of ALT had little difference with the serious of dehydration. Conclusion The patients of rotavirus diarrhea often occur liver lesion. There is no relation between the liver lesion with the serious dehydration. The younger of the age, the higher rate of unfuction of liver.

关 键 词：轮状病毒感染 肠炎 肝脏损害 

分 类 号：R725.1[医药卫生—儿科]