电场辐照前后某些中药有效成分的质谱分析  

Mass Spectrometric Analysis of Some Active Components of Traditional Chinese Medicine Before and After Field Radiation

作　　者：宋凤瑞[1] 周雨[1,2] 刘淑莹 王希路[3] 

机构地区：[1]中国科学院长春应用化学研究所 [2]长春130022 [3]东北师范大学物理系

出　　处：《分析化学》1997年第10期1148-1152,共5页Chinese Journal of Analytical Chemistry

基　　金：吉林省科委青年基金

摘　　要：利用快原子轰击质谱（ＦＡＢＭＳ）及解吸电子轰击质谱（ＤＥＩＭＳ）方法，分析了电场辐 照前后的５种中药有效成分，证明电场辐照灭菌并不改变其化学结构。讨论了底物效应及正、 负快原子轰击质谱的差异，以及与解吸电子轰击质谱的不同断裂规律，同时利用Ｂ／Ｅ联动扫 描（亚稳离子测定）进行了验证。Five active components of traditional Chinese medicine have been studied by means of fast atom bombardment (FAB) and desorption electron impact (DEI) mass spec- trometry. It has been proved that the structures of these active components have not been changed after electric field irradiation for sterilization. The fragmentation mechanisms for the DEI mass spectra have been discussed and the cleavage pathways were confirmed by us- ing the B/E linked scanning method.

关 键 词：中药 电场辐照 质谱分析 FABMS DEIMS 

分 类 号：R284.1[医药卫生—中药学]