继发性不育男性泌尿生殖道支原体感染状况与耐药性分析  

Analysis of infections and drug resistance of mycoplasmas in urogenital system of secondary infertile males

作　　者：谢小毛[1] 黄开淑[1] 李文华[1] 陈红娟[1] 张文权[1] 胡兰英[1] 

机构地区：[1]常德市第一人民医院生殖医学中心,湖南常德415003

出　　处：《中国男科学杂志》2008年第9期48-50,共3页Chinese Journal of Andrology

摘　　要：目的探讨继发性不育男性患者泌尿生殖系支原体的感染状况及其耐药性。方法采用支原体分离培养鉴定与药敏试剂盒,对继发性不育男性患者泌尿生殖系分泌物进行支原体分离培养鉴定与药敏测试。结果572例继发性不育男性患者,泌尿生殖系支原体培养阳性278例,阳性率为48.6%,其中解脲脲原体(Uu)占90.3%(251/278);人型支原体(Mh)占1.4%(4/278);Uu合并Mh占8.3%(23/278)。药敏试验表明:喹诺酮类耐药率最高,四环素类和大环内酯类耐药率最低。结论支原体感染是男性继发不育的重要危险因素,在支原体感染的治疗过程中,我们应根据药敏测试结果选择敏感抗生素。Objective To analyze the mycoplasmal infection and its drug resistance in the urogenital system of infertile males. Methods Mycoplasma was cultured and identified in the discharge from urogenital system of secondary infertile male,then its drug resistance was test by drugsusceptibility kit. Results Mycoplasma culture were found to be positive in 278 patients（48.6%）, Among them,Ureaplasma urealyticum （Uu）infection account for 90.3% （251/278）, Mycoplasma hominis（Mh） infection for 1.4%（4/278）and the combination of Uu and Mh for 8.3%（23/278）; The drug resistance test show that mycoplasma was the most susceptibility to macrolides and tetracyclines, but in susceptibility to fluoroquinlones. Conclusion Ureaplasma urealyticum infection isan important risk factor in Secondary infertility of males, therefore, the susceptible antibiotics shoud be chosen according to the susceptibility test in the treatment of mycoplasmal infections.

关 键 词：男性 继发性不育 支原体 感染 耐药 

分 类 号：R698.2[医药卫生—泌尿科学] R518.2[医药卫生—外科学]