罗丹明B-β-环糊精衍生物探针型主-客体分子相互识别作用的研究  

Molecular Recognition Between Rhodamine B-(alkylamino)cyclodextrin Complexes Probe Type Host Molecule and the Guest Molecule

作　　者：冯喜增[1] 邢婉丽[1] 曹瑛[1] 何锡文[1] 

机构地区：[1]南开大学化学系

出　　处：《高等学校化学学报》1997年第10期1637-1641,共5页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金;国家教委博士点基金

摘　　要：应用光谱法研究了生物大分子探针型主体分子罗丹明B一β-环糊精衍生物与DNA的相互作用及温度对该探针特性的影响.探讨了相应的主体分子与DNA分子相互作用的方式、嵌插作用能力大小以及温度对主体分子含客体分子时的影响．进一步研究了探针型主一客体分子相互识别作用及作用能力的大小．探讨了主一客体分子相互识别作用的机制．in this paper, we have studied the interaction between a nenthesized probe type host molecule, RhB-β-CDcn, and DNA as well as the effect of temperature upon thefunction of this probe using spectrum method. The mode of the interaction between probemolecule and DNA, the ability of their intercalation and the effect of temperature upon hostmolecule containing guest molecule were discussed. In addition, the mechanism ofrecognition between the host molecule and the guest molecules was also studied.

关 键 词：罗丹明B Β-CD DNA 识别 主体 药物载体 客体 

分 类 号：R966[医药卫生—药理学] Q523[医药卫生—药学]