外关穴真、假针刺fMRI脑功能成像研究  

An fMRI Cerebral Functional Imaging Study on True/Sham Needling in Waiguan(SJ5)

作　　者：赖新生[1] 曾统军[2] 黄泳[2] 张贵锋[2] 单保慈[3] 邹燕齐[2] 李赣龙[2] 吴俊贤[2] 

机构地区：[1]广州中医药大学针灸推拿学院经络原理研究室,广东广州510407 [2]南方医科大学中医药学院针灸教研室,广东广州510515 [3]中国科学院高能物理研究所核分析研究室,北京100049

出　　处：《中国中医基础医学杂志》2008年第9期705-708,共4页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：国家重点基础研究发展计划(973计划)资助项目(2006CB504505);国家自然科学基金重大研究计划项目(90709027)

摘　　要：目的:运用fMRI脑功能成像技术,研究外关穴真针刺、假针刺不同状态下,青年志愿者不同脑区的激活情况,以印证"经穴特异性-脑相关假说"。方法:12例健康志愿者随机分为外关穴真针刺和假针刺组,分别接受不同的刺激。同时,运用GE公司3.0T超导MRI系统完成脑部扫描。所得图像采用SPM2软件包进行处理和分析。结果:外关穴真针刺能显著激活BA45、374、4、40、22、13、37、47区、海马、杏仁核、黑质等区域,外关穴假针刺则能显著激活BA46、44、41、13、40、37、19区等区域,与假针刺对比,外关穴真针刺能显著激活BA8区和小脑等区域,在一定程度上印证了赖新生教授的"经穴特异性-脑相关学说"。Objective： The effects of true or sham needling in Waiguan （SJ5） in young healthy volunteers were observed by fMRI cerebral functional imaging in order to prove the hypothesis of “Acupoint-specific has close relationship with the brain”. Method： Twelve young healthy volunteers were divided into 2 groups randomly and received the different stimulations of true or sham needling in SJ5 respectively. In the mean time, GE 3.0T MRI was used to make a cerebral scan and the collected pictures were analyzed by SPM2. Results： True needling in SJ5 could significantly activate the areas of BA45, 37, 44, 40, 22, 13, 37, 47 and Hippocampus, Amygdala and Substania Nigra, while sham needling in SJ5 could significantly activate the areas of BA46, 44, 41, 13, 40, 37 and 19. Compared with the sham needling, true needling in SJ5 could activate the areas of BA8 and cerebellum, which prove the hypothesis of “Aeupoint-specific has close relationship with the brain” in a certain degree.

关 键 词：外关穴 腧穴特异性 针刺 FMRI 脑功能成像 

分 类 号：R246[医药卫生—针灸推拿学]