109例不孕妇女血清抗透明带抗体检测结果分析  

Analysis of the AzpAb Detection of 109 Women of Infertility

作　　者：常笑雪[1] 黄鹂[1] 张鑫[1] 杨石强[1] 

机构地区：[1]河南科技大学医学院解剖与组织胚胎学教研室,洛阳471003

出　　处：《中国计划生育学杂志》2008年第10期622-623,共2页Chinese Journal of Family Planning

摘　　要：目的:探讨抗透明带抗体(AzpAb)在不孕症中的作用。方法:用ELISA间接法测定109例不孕妇女(包括原发和继发不孕)血清的AzpAb,47例早孕妇女做对照。结果:109例不孕妇女中AzpAb阳性者21例,阳性率为19.3%;47例对照组阳性1例,阳性率为2.1%,差异有统计学意义(P<0.01)。23～30岁组77例中AzpAb阳性者14例,阳性率18.2%;31～42岁组32例中AzpAb阳性者7例,阳性率21.9%。原发不孕组48例中AzpAb阳性者10例,阳性率20.8%;继发不孕组61例中AzpAb阳性者11例,阳性率18%。差异无统计学意义(P>0.05)。结论:Az-pAb可以导致原发或继发不孕,且与年龄无关。Objective ： To identify the roles of AzpAb in infertilitas feminis. Methods： Serum AzpAb of these 109 women of infertility （including both primary and secondary infertility） were determined using ELISA indirect method, and 47 early pregnant women were brought into this study as a control group. Results： 21 cases （19.3%） of positive results were detected among the 109 infertile women, and only 1 case （2.1%） was detected among the control group, with the difference was statistically significant （ P 〈 0.01 ）. 14 cases （ 18.2% ） of positive results were detected among the 77 cases of the 23 - 30 years old group, and 7 cases （21.9%） among the 32 cases of the 31 -42 years old group. 10 cases （20.8%） were detected in the primary infertility group （48 cases）, and 11 cases （18%） in the secondary infertility group （61 cases）. The difference was not statistically significant （ P 〉 0. 05 ）. Conclusion ： AzpAb can lead to primary and secondary infertility, independent of the age.

关 键 词：不孕 抗透明带抗体 酶联免疫吸附实验 

分 类 号：R711.6[医药卫生—妇产科学] R446.112[医药卫生—临床医学]