肝移植术后早期精神并发症病因分析  

Etiological Analysis and Treatment of Early Psychiatric Complications in Patients after Liver Transplantation

作　　者：许幂[1] 齐海智[1] 贺志军[1] 胡伟[1] 司中洲[1] 李一宁[1] 

机构地区：[1]中南大学湘雅二医院普外器官移植科,湖南长沙410011

出　　处：《医学临床研究》2008年第10期1757-1758,1762,共3页Journal of Clinical Research

摘　　要：【目的】探讨肝移植术后早期患者出现精神并发症的原因及诊治经验。【方法】回顾性分析本院近3年47例肝移植患者病例资料,总结术后出现精神并发症的原因,诊断及治疗措施。【结果】47例患者中有13例出现精神并发症,最早出现于术后d3,最晚术后d15;其中表现为睡眠障碍者11例,躁狂5例,幻视2例,抑郁5例,自杀倾向2例;若术前即存在肝性脑病术后则易出现精神并发症;精神并发症的出现还可能与免疫抑制剂的使用,手术时间的长短以及术后患者内环境和外环境的状态有关。【结论】肝移植术后早期出现的精神并发症多无神经系统的器质性病变,症状较轻,通过对症处理预后较好。[Objective]To explore the etiopathogenisis and treatment of early psychiatric complications in patients after liver transplantation. [Methods] A retrospective study was made by analyzing the clinical data of 47 cases of liver transplantation in our hospital in recent 3 years to summarize the etiopathogenisis, diagnosis and treatment of psychiatric complications. [＇Results]There were 13 of 47 cases who occurred psychiatric complications during the 3rd day to the 15th day after operation, including 11 cases with sleep disorder, 5 case with vesania, 2 cases with hallucinosis,5 cases with depression and 2 cases with suicidal tendency. The patients who suffered from hepatic encephalopathy were prone to have those psychiatric complications. The occurrence of psychiatric complications was probably related to the usage of immunodepressive, duration of the operation and the condition of internal and extrinsic environment of the patients. [Conclusion]Most of the early psychiatric complications after liver transplantation may not result from neurologie structural diseases, and the symptoms are usually light. There will be good outcome after treatment against the symptoms.

关 键 词：肝移植 手术后并发症 精神病/病因学 

分 类 号：R657.3[医药卫生—外科学]