体描法与一口气法测定正常人和COPD病人FRC的比较  

Comparative Study on Plethysmography and Single-breath Method for Detecting Lung Functional Residual Capacity in Healthy People and COPD Patients

作　　者：王杨[1] 罗秀芳[1] 赖莉芬[2] 

机构地区：[1]首都医科大学附属北京同仁医院呼吸内科,北京100730 [2]海军总医院,北京100009

出　　处：《医学临床研究》2008年第10期1820-1821,共2页Journal of Clinical Research

摘　　要：【目的】探讨慢性阻塞性肺疾病(COPD)病人是否能采用弥散一口气法测定功能残气量。【方法】同时用体积描记法和弥散一口气法测定32例健康人,23例COPD病人的胸腔气量(TGV)或功能残气量(FRC)及肺总量(TLC)或肺泡量(VA)等肺容量指标。【结果】正常组用两种方法测量FRC差异无显著性(P>0.05)而TLC差异有显著性(P<0.01)。而在COPD组两方法比较FRC、TLC差异均有极显著性(P<0.01)。【结论】对于正常人可采用弥散一口气法粗略估算FRC,但不能作为实测值。而COPD病人不能采用弥散一口气法测定FRC。[Objective] To investigate the availability of diffusion single-breath method for detecting lung functional residual capaeity（FRC） in patients with chronic obstructive pulmonary disease（COPD）. [Methods] Plethysmography and single-breath method were used simultaneously to detect lung capacity index such as thoracic gas volume（TGV）/FRC and total lung capacity （TLC）/volume of alveolus （VA）, in 32 healthy people （control group） and 23 COPD patients（COPD group）. [Results] Between the two methods, there was no significant difference in FRC （P〉0.05）, but there was significant difference in TLC （ P〈0, 01） in control group, while there was remarkable difference in both FRC and TLC in COPD group（ P〈0.01）. [Conclusion] Single-breath method can be used in healthy people to approximately estimate FRC, which can not be regarded as factual data. However single-breath method cannot be used in COPD patients for FRC detection.

关 键 词：肺疾病 阻塞性 慢性病 功能残气量 

分 类 号：R563.9[医药卫生—呼吸系统]