广西贺州城镇成人慢性肾脏病的流行病学调查  

Epidemiologic investigation of chronic kidney disease in adult urban population of Hezhou Guangxi

作　　者：廖蕴华[1] 潘玲[1] 陈青云[2] 黄莉[1] 霍冬梅[1] 宋雅珊[1] 陈莹[2] 唐曦平[1] 马健皓[1] 彭育欢 陈强文 苏飞群 周翠屏 黎水莲 

机构地区：[1]广西医科大学第一附属医院肾内科,南宁530021 [2]广西医科大学第一附属医院内分泌科,南宁530021 [3]广西贺州市人民医院内科

出　　处：《中华肾脏病杂志》2008年第10期701-705,共5页Chinese Journal of Nephrology

基　　金：国家自然科学基金（30260042）

摘　　要：目的探讨广西贺州城镇成人慢性肾脏病（CKD）的患病情况及危险因素。方法在广西中小城市贺州，采用分层整群系统随机抽样的方法，抽取贺州部分城镇1200名18岁以上的常住居民，对其进行问卷调查、检测肾脏损伤指标及相关危险因素。结果在资料完整的1069名居民中，白蛋白尿的患病率为7．5％；血尿的患病率为4．8％，肾功能下降的患病率为3．6％。该人群CKD的患病率为14．4％，知晓率为1．4％。二分类Logistic回归分析提示，年龄（OR为1．022，95％CI为1．008～1．035）、性别（OR为2．249，95％CI为1．502～3．367）、高血压（OR为4．397，95％CI为2．601—7．432）及糖尿病（OR为7．422，95％CI为3．985～限825）与CKD独立相关。结论在我国广西中小城市贺州部分城镇中，成人CKD的患病率为14．4％，知晓率为1．4％。CKD的相关危险因素包括年龄、性别、高血压及糖尿病，与发达国家和我日大城市相似。Objective To investigate the prevalence and risk factors of chronic kidney disease （CKD） in the adult urban population of Hezhou Guangxi. Methods One thousand and two hundred urban residents （older than 18 years） from Hezhou Guangxi were randomly selected using a random sampling. All the residents were interviewed. Their morning spot urine were tested to determine albumin to creatinine ratio （abnormal： ≥30 mg/g）, and renal function [abnomal： eMDRD 〈60 ml·min^-1（1.73 m^2）^-1] was assessed. Morning spot urine dipstick of hematuria （abnormal： ≥1 ＋ ） was confirmed by microscopy （abnormah 〉 3 red blood cells/HP）. The associations among demographic characteristics, health characteristics and indicators of kidney damage were examined. Results Eligible data of 1069 subjects were enrolled in the study. The prevalence of albuminuria was 7.5%, hematuria 4.8%, and redueed eGFR 3.6%. The prevalence of kidney disease was 14.4% and the recognition was 1.4%. Age （OR 1.022, 95%CI 1.008-1.035）, gender （OR 2.249, 95%CI1.502-3.367）, diabetes mellitus （OR 7.422, 95%CI 3.985-13.825） and hypertension （OR 4.397, 95% C1 2.601-7.432） were independently associated with CKD. Conclusions The prevalence of chronic kidney disease is 14.4% and the recognition is 1.4% in aduh urban population of Hezhou Guangxi. Independent risk factors associated with chronic kidney disease are age, gender, diabetes mellitus and hypertension which is similar to those in developed countries and domestic big cities.

关 键 词：肾疾病 流行病学 患病率 危险因素 

分 类 号：R692[医药卫生—泌尿科学] R595.7[医药卫生—外科学]