MRI对实验性闭袢性小肠梗阻肠壁缺血评估的价值  

The Experimental Study on Small Bowel Ischemia in Closed Loop Obstruction with MRI Scanning

作　　者：宣家文[1,2] 翟建[1] 陈远军 张峥嵘[1] 丁治民[1] 汪向明[3] 

机构地区：[1]皖南医学院附属弋矶山医院影像科,安徽芜湖241001 [2]安徽省立友谊医院影像科,230011 [3]皖南医学院附属弋矶山医院病理科,安徽芜湖241001

出　　处：《临床放射学杂志》2008年第10期1414-1418,共5页Journal of Clinical Radiology

基　　金：安徽省教育厅省级自然科学研究项目(编号:KJ2007B286)

摘　　要：目的探讨MRI多序列扫描对实验性闭袢性小肠梗阻肠壁缺血的诊断价值。材料与方法24只大白兔实验性闭袢性小肠梗阻模型分为3组，每组8只：A组（缺血1～1．5h）、B组（缺血2～2．5h）和C组（缺血5～6h），对照肠壁组织病理改变分析MRI表现。结果A组、B组和C组测量的肠壁厚度分别是（0．135±0．033）cm、（0．185±0．030）cm、（0．383±0．060）cm，肠壁厚度之间的差异有统计学意义（P〈0．05）。A组8只、B组5只闭袢肠壁增强扫描出现持续强化，C组闭袢肠壁均无强化。肠壁无坏死组出现持续强化征象明显高于肠壁坏死组（P〈0．05）。结论MRI多序列扫描可评价肠壁不同时间的缺血。Objective To investigate ischemia of the bowel in experimental closed loop obstruction model with MRI. Materials and Methods 24 rabbits with experimental closed loop obstruction model were divided into three groups with each group containing 8. Ischemia for 1 - 1.5 hours was defined as group A, isehemia for 2 - 2.5 hours was defined as group B, and ischemia for 5 - 6 hours was defined as group C. MR imaging findings were analysed correlated with pathological findings. Results The thickness of the bowel wall in 3 groups was （0. 135±0.033） cm, （0. 185 ±0.030） cm, and （0. 383 ± 0. 060）cm, respectively. There was significant difference in the thickness of the bowel wall between 3 groups （P 〈 0.05 ）. On postcontrast T1WI, enhancement of the bowel wall was seen in eight rabbits of group A and five rabbits of group B and no enhancemeng of the bowel wall was found in group C. The detection rate of enhancement in rabbits without necrotic closed loop was higher than that in rabbits with necrotic closed loop （ P 〈 0.05 ）. Conclusion The ischemia of the closed loop bowel wall could be evaluated on MRI images.

关 键 词：小肠梗阻 磁共振成像 动物 

分 类 号：R656.7[医药卫生—外科学] R445.2[医药卫生—临床医学]