单纯性Rathke囊肿患者内分泌功能改变的初步研究  

Preliminary study of endocrine dysfunction in patients with Rathke＇s cleft cyst

作　　者：魏广玉[1] 吕朝晖[1] 窦京涛[1] 母义明[1] 陆菊明[1] 

机构地区：[1]解放军总医院内分泌科,北京100853

出　　处：《中华内分泌代谢杂志》2008年第5期489-490,共2页Chinese Journal of Endocrinology and Metabolism

摘　　要：回顾性分析65例单纯性Rathke囊肿患者手术前后内分泌功能改变，术前存在的垂体激素分泌异常以垂体一性腺激素分泌受损和高催乳素血症多见，最常见症状女性为月经紊乱及溢乳、男性为性欲减退及勃起功能障碍，严重者可发生全垂体功能减退甚至危象。手术可以有效改善受损的垂体功能，也可能导致新的损害。A retrospective study of endocrine dysfunction in 65 patients with Rathke＇s cleti cyst （RCC） was conducted. Before surgical operation, most patients with RCC had various degrees of pituitary dysfunction. Impaired gonadotropin secretion and prolactinemia were the prevalent abnormalities. Erectile dysfunction or diminished libido in male and menstrual disorder or galactorrhea in female were frequently seen. The panhypopituitarism appeared in a few patients with RCC. The patients would benefit by surgical removal, however, attention should be paid to avoid new damage of the pituitary gland during operation.

关 键 词：RATHKE囊肿 内分泌功能紊乱 垂体 手术 

分 类 号：R651.13[医药卫生—外科学]