八种蜂花粉醇提物对酪氨酸酶的二酚氧化活性的抑制作用  

Inhibitory Effects of Ethanolic Extracts from Eight Kinds of Bee Pollens on the Activity of Tyrosinase to Oxidize Diphenol

作　　者：张红城[1,2] 董捷[1,2] 尹策[1,2] 

机构地区：[1]中国农业科学院蜜蜂研究所,北京100093 [2]农业部国家蜂产品加工专业分中心,北京100093

出　　处：《天然产物研究与开发》2008年第5期880-883,共4页Natural Product Research and Development

基　　金：农业部公益性行业(农业)科研专项经费项目(ny-hyzx07-041);农业部基本科研业务费专项课题(200703);中国农业科学院蜜蜂研究所研发基金(200702)

摘　　要：本文研究了杏花花粉、茶花花粉、油菜花粉、向日葵花粉、荷花花粉、荞麦花粉、玫瑰花粉、五味子花粉等八种花粉醇提物对酪氨酸酶的二酚氧化活性的抑制作用。结果表明这八种花粉醇提物对以L-多巴为底物的酪氨酸酶抑制作用,存在显著性差异。其中向日葵花粉醇提物表现出最好的抑制作用,IC50为(0.303±0.003)mg/mL,五味子花粉醇提物的抑制作用相对较弱,IC50为(1.946±0.045)mg/mL。Ethanolic extracts from eight kinds of bee pollens were assessed whether to have inhibitory effects on the activity of tyrosinase which substrates were L-DOPA, which were apricot pollen, camellia pollen, rape pollen, sunflower pollen,lotus pollen, buckwheat pollen, rose pollen and schisandra pollen. The results indicated that there are significant differences of inhibitory activities on tyrosinase among ethanolie extracts. Ethanolic extracts of sunflower pollen had the strongest inhibitory activity,which IC50 was （0.303 ± 0. 003 mg/mL. But ethanolic extract of schisandra pollen had the weakest activity,which IC50 was（ 1. 946 ±0. 045 ） mg/mL.

关 键 词：蜂花粉 醇提物 酪氨酸酶 抑制作用 

分 类 号：R282.71[医药卫生—中药学] Q946.91[医药卫生—中医学]