回声追踪技术发现高血压患者早期的颈动脉弹性变化  

Early Detection of Carotid Decreased Elasticity by Echo-Tracking Technology in Essential Hypertension Patients

作　　者：赵金惠[1] 赵真[1] 刘凤华[2] 

机构地区：[1]河北大学附属医院功能科,河北保定071000 [2]河北农业大学医院功能科,河北保定071000

出　　处：《中华高血压杂志》2008年第10期885-888,共4页Chinese Journal of Hypertension

摘　　要：目的探讨回声追踪技术(Echo-Tracking)检测原发高血压患者颈动脉弹性的应用价值。方法根据颈动脉超声的检查结果,把原发高血压(EH)患者82例分为两组:颈动脉异常组(EH+颈动脉有斑块,n=43),患者有一侧或双侧颈动脉内中膜增厚和(或)斑块存在;颈动脉正常组(EH+颈动脉无斑块组,n=39),双侧颈动脉内膜中膜无增厚且无斑块存在。另选正常人作为健康对照组(健康组)50例。用回声追踪技术自动跟踪颈总动脉壁的运动,并检测以下参数:收缩期颈总动脉管径(Ds)、舒张期颈总动脉管径(Dd)、压力—应变弹性系数(E_ρ)、硬化参数(β)、顺应性(AC)、脉搏波传导速度(PWVβ)和增大指数(AI)。结果 EH+颈动脉有斑块组和 EH+颈动脉无斑块患者组的 E_ρ(EH+颈动脉有斑块组:219.2±60.5,EH+颈动脉无斑块组:140.6±51.5比健康组:90.5±23.9,P<0.01)、β(EH+颈动脉有斑块组:16.1±7.8,EH+颈动脉无斑块:13.1±4.0比健康组:8.3±3.0,P<0.01)、PWVβ(EH+颈动脉有斑块组:8.38±1.13,EH+颈动脉无斑块组:7.14±0.92比健康组:5.94±0.65,P<0.05)、AI(EH+颈动脉有斑块组:19.07±9.97,EH+颈动脉无斑块:18.86±6.83比健康组:12.45±4.59,P<0.01)都较健康组显著增加,AC(EH+颈动脉有斑块组:0.70±0.17,EH+颈动脉无斑块组:0.74±0.26比健康组:0.88±0.22,P<0.05)较健康组显著减低,Ds(EH+颈动脉有斑块组:7.94±1.35,EH+颈动脉无斑块组:8.02±1.28比健康组:7.50±1.20,P<0.05)和 Dd(EH+颈动脉有斑块组:7.63±1.19,EH+颈动脉无斑块:7.60±1.22比健康组:7.01±1.01,P<0.05)显著增宽。结论 EH 患者在颈动脉出现内膜中膜增厚或斑块之前,动脉弹性已经发生了变化。回声追踪技术可用来检查动脉硬化早期的动脉弹性改变。Objective To evaluate E-Tracking technology in detecting early elasticity changes in the carotid artery in essential hypertension （EHI patients. Methods Eighty-two cases of EH patients were categorized according to the finding of B-mode uhrasonography of carotid artery： abnormal carotid group （n=43） with intima media thickning and/or with plaques in one or both sides; normal carotid group（n=39）; normal healthy subjects （n= 50） were selected as controls. Eeho-Tracking（E-T） technology was performed to follow the movement tracks of the common carotid arterial wall. Systolic diameter of common carotid artery（Ds） , diastolic diameter of common carotid artery （ Dd） , pressure-strain elastic modulus（ Eρ） , stiffness parameter（β） , arterial compliance（ AC ）, pulse wave conducting velocity （PWVβ） and augment index（AI） were determined by echo-tracking examination. Results The parameters showing in decreased elasticity of artery, Eρ（ abnormal carotid ： 219.2 ± 60.5, normal carotid： 140.6 ± 51.5 vs control： 90.5±23.9, P〈0.01） , β（abnormal carotid： 16.1±7.8, normal carotid： 13.1±4.0 vs control： 8.3±3.0, P〈0.01）, PWVβ（abnormal carotid： 8.38±1. 13, normal carotid： 7.14±0.92 vs control： 5.94±0.65, P〈0.05）, AI（abnormal carotid： 19.07±9.97, normal carotid： 18.86±6.83 vs control： 12.45±4.59, P〈0. 01） were all increased, while dimension of carotid artery, as Ds（abnormal carotid： 7.94±1.35, normal carotid： 8. 02±1.28 vs control： 7.50± 1.20, P〈0.05） and Dd （abnormal carotid： 7.63± 1.19, normal carotid： 7.60± 1.22 vs control： 7.01 ± 1.01, P〈0. 05） were increased concomitantly associated with lower AC （abnormal carotid： 0.70± 0.17, normal carotid： 0.74 ± 0.26 vs control： 0.88 ± 0.22, P〈0.05）. Conclusion The elasticity of the carotid artery in EH was changed before the occurrence of intima-media thickning or plaques. The Echo-Tracking technol- ogy can be used to detect the early el

关 键 词：回声追踪技术 原发性高血压 颈动脉 超声检查 

分 类 号：R544.1[医药卫生—心血管疾病] R543[医药卫生—内科学]