Network of tRNA Gene Sequences  

作　　者：韦芳萍 李晟 马红孺 

机构地区：[1]Department of Physics, Guangxi University, Nanning [2]Institute of Theoretical Physics, Shanghai Jiaotong University

出　　处：《Journal of Shanghai Jiaotong university(Science)》2008年第5期611-616,共6页上海交通大学学报（英文版）

基　　金：the National Natural Science Foundation of China (Nos. 10105007, 10334020, 90103035,10574088)

摘　　要：A network of 3719 tRNA gene sequences was constructed using simplest alignment. Its topology, degree distribution and clustering coefficient were studied. The behaviors of the network shift from fluctuated distribution to scale-free distribution when the similarity degree of the tRNA gene sequences increases. The tRNA gene sequences with the same anticodon identity are more self-organized than those with different anticodon identities and form local clusters in the network. Some vertices of the local cluster have a high connection with other local clusters, and the probable reason was given. Moreover, a network constructed by the same number of random tRNA sequences was used to make comparisons. The relationships between the properties of the tRNA similarity network and the characters of tRNA evolutionary history were discussed.A network of 3719 tRNA gene sequences was constructed using simplest alignment. Its topology, degree distribution and clustering coefficient were studied. The behaviors of the network shift from fluctuated distribution to scale-free distribution when the similarity degree of the tRNA gene sequences increases. The tRNA gene sequences with the same anticodon identity are more self-organized than those with different anti- codon identities and form local clusters in the network. Some vertices of the local cluster have a high connection with other local clusters, and the probable reason was given. Moreover, a network constructed by the same number of random tRNA sequences was used to make comparisons. The relationships between the properties of the tRNA similarity network and the characters of tRNA evolutionary history were discussed.

关 键 词：similarity network transfer ribonucleic acid gene degree distribution clustering coefficient 

分 类 号：O414.2[理学—理论物理]