毛鸡骨草对高血脂大鼠抗氧化性能的研究  

The Dilot study Antioxidant Activity for the Hyperlipidemia rats of Abrus mollisHance

作　　者：甘耀坤[1] 陈晓白[1] 韦巧春[1] 彭素娜[1] 周艳[1] 李瑗昌[1] 

机构地区：[1]玉林师范学院化学与生物系,教授广西玉林537000

出　　处：《玉林师范学院学报》2008年第3期72-75,共4页Journal of Yulin Normal University

基　　金：广西科技厅自然基金项目(No.桂科自0728250);广西教育厅科研项目(No.教育厅200710MS052)

摘　　要：目的:研究毛鸡骨草抗氧化性能及对高血脂氧化损伤的保护作用.方法:将实验大鼠分成三组:高血脂病理组(即模型组)、毛鸡骨草低剂量组(10g/kg)、毛鸡骨草高剂量组(20g/kg),经过相同时间处理后,检测各组大鼠心肌和肾脏超氧化物歧化酶(SOD)活性和丙二醛(MDA)含量,然后进行比较.结果:毛鸡骨草低剂量组和高剂量组大鼠的心肌及肾脏SOD活性与模型组相比均出现显著上升(P<0.05),而MDA含量均呈现明显下降(P<0.05);但在高、低剂量组两者之间没有显著性差异(P>0.05).结论:毛鸡骨草能降低高血脂大鼠心肌、肾脏MDA含量和提高SOD活性,对高血脂大鼠具有一定抗氧化的作用.Purpose： To pilot study antioxidant activity and the effect of mechanism for the Hyperfipidemia rats of Abrus mollisHance, so as to discuss Abrus mollisHance＇s value in health function. Methods： the big rat were divided into three groups： hight blood fat set （model set）, low doses set （10g/kg）. hight Abrus mollisHance set （ 20g/kg ） , After treat with in the same time, measure the activity of SOD and the level of MDA, and then process comparatively. Results： The activity of SOD of low Abrus mollisHance set and hight doses set cardiac muscle and was significantly higher than the model set（P〈0.05） ; the levels of MDA was significantly lower than the model set （P〈0.05）, but there is no obvious difference between hight Abrus mollisHance set and low doses set obviously （P〉0.05）. Conclution： Abms mollisHance can reduce the high fat rat heart, kidney MDA content and enhance the activity of SOD, have antioxidize on the big rat in hight blood fat.

关 键 词：毛鸡骨草 高血脂 抗氧化性能 

分 类 号：Q949.95[生物学—植物学]