孔雀石绿胁迫下鲫肝脏抗氧化系统的动态变化  

Dynamic Changes of Antioxidant System in Liver of Crucian Carp Exposed to Malachite Green

作　　者：陈晓妮[1] 吴志强[1] 王玉彬[1] 

机构地区：[1]南昌大学生命科学学院,江西南昌330031

出　　处：《江西科学》2008年第5期711-713,756,共4页Jiangxi Science

基　　金：2004年江西省科技厅重大招标项目;南昌市科技局三项攻关项目(z04036)。

摘　　要：以鲫(carassius auratus)幼鱼为实验对象,研究在不同浓度孔雀石绿胁迫下,肝脏抗氧化防御系统中过氧化氢酶(CAT),超氧化物歧化酶(SOD)和谷胱甘肽-S-转移酶(GST)的活性变化趋势。结果表明,SOD和CAT活性变化规律较复杂,但始终低于对照组;而GST活性先被抑制后被激活,最终略高于对照组。3种酶对孔雀石绿暴露的敏感性顺序为SOD>CAT>GST。This paper utilized Crucian carp （carassius auratus） as the experimental materials and studied the activity change trend of catalase （CAT）, superoxide dismutase （SOD） and glutathione - S - transferase （GST） in the liver antioxidant defense system in exposure to different concentrations of malachite green. The results showed that the activity change law of SOD and CAT were relatively complicated;they were always lower than the control group. While GST was first inhibited and then activated, finally it was slightly higher than the control group. Exposed to malachite green, the sensibility order of these three is SOD 〉 CAT 〉 GST.

关 键 词：孔雀石绿 鲫 超氧化物歧化酶 过氧化氢酶 谷胱甘肽-S-转移酶 

分 类 号：R512.6[医药卫生—内科学]