1-苯基-5-芳基-1，2-二氢-1，2，4-三唑-3-硫酮的合成  

Synthesis of 1-Phenyl-5-aryl-1,2-dihydro-1,2,4-triazole-3-thione Derivatives

作　　者：刘天宝[1] 彭艳芬[1] 邹建平[2] 

机构地区：[1]池州学院化学与食品科学系,池州247000 [2]苏州大学化学化工学院,苏州215123

出　　处：《有机化学》2008年第10期1813-1815,共3页Chinese Journal of Organic Chemistry

基　　金：安徽省教育厅自然科学基金(No.2006KJ156B)资助项目.

摘　　要：将取代苯甲酰氯1a～1f与硫氰酸钾反应,得到的中间体不需纯化直接与苯肼反应,成功地合成了1-苯基-5-芳基-1,2-二氢-1,2,4-三唑-3-硫酮(2a～2f).化合物2的结构通过红外光谱、核磁共振光谱和高分辨质谱进行了表征.Substituted benzoyl chlorides were reacted with potassium isothiocyanate, and the resulting intermediates were then reacted with phenyl hydrazine to give the title compounds 1-phenyl-5- aryl-1,2-dihydro-1,2,4-triazole-3-thione derivatives. Their structures were characterized by IR, 1H NMR, 13C NMR and HRMS data.

关 键 词：-1 2 4-3(2H)-硫酮 取代苯甲酰氯 苯肼 

分 类 号：O626.2[理学—有机化学]