钉螺感染日本血吸虫后酸性磷酸酶含量变化  

Changes of contents of acid phosphatase in Oncomelania snails infected with Schistosoma japonicum

作　　者：刘凌鹏[1] 肖丽波[1] 何昌浩[2] 冯清[1] 

机构地区：[1]华中科技大学化学与化工学院,武汉430030 [2]华中科技大学同济医学院病原生物学系

出　　处：《中国血吸虫病防治杂志》2008年第5期367-368,F0003,共3页Chinese Journal of Schistosomiasis Control

基　　金：湖北省卫生厅科研基金(JX2B01;NX200505);湖北省科技攻关项目(2005AA401C30)

摘　　要：目的观察钉螺感染日本血吸虫后酸性磷酸酶(ACP)含量的变化。方法以软组织挤压法获取感染性钉螺与阴性钉螺血淋巴细胞涂片,分别对2组钉螺血淋巴细胞进行ACP组织化学染色,用显微镜观察其活性变化。结果感染性钉螺淋巴细胞中ACP含量增加,明显高于阴性钉螺。结论ACP可能在钉螺感染日本血吸虫毛蚴的防御中发挥作用。Objective To observe the contents of acid phosphatase （ACP） of Oncomelania snails infected with Schistosma japonicum. Methods Both the blood lymphocytes of positive and negative Oncomelania snails were dyed with the histochemistry staining method and their ACPs were observed under a microscope. Results The contents of ACP in the positive Oncomelania snails increased, being significantly higher than those in the negative snails. Conclusion The contents of ACP increase in Oncomelania snails infected with Schistosoma japonicum and ACP may have the defence function.

关 键 词：钉螺 日本血吸虫 酸性磷酸酶 

分 类 号：R383.24[医药卫生—医学寄生虫学]