Two new lignans from Dipteronia dyeriana  

作　　者：Rong Guo Min Luo Chun Lin Long Ma Lin Li Zhi Qin Ouyang Yi Ping Zhou Yue Hu Wang Xing Yu Li Ya Na Shi 

机构地区：[1]Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China [2]Yunnan Agricultural University, Kunming 650201, China [3]Yunnan Laboratory of Pharmacology for Natural Products, Kunming Medical College, Kunming 650031, China [4]Yunnan Introduction ＆ Propagation Center for Rare ＆ Endangered Plants, Kunming 650032, China

出　　处：《Chinese Chemical Letters》2008年第10期1215-1217,共3页中国化学快报（英文版）

基　　金：the Ministry of Science and Technology of China(2005DKA21006);the Knowledge Innovation Project of Chinese Academy of Sciences.

摘　　要：A new sesquilignan, 7＇,8＇-didehydroherpetotriol （1）, and a new lignan glycoside, （＋）-isolariciresinol-9＇-O-α-L-rhamnopyra- nosy1-（1→6）-[3-D-glucopyranoside （2）, were isolated from the branches of Dipteronia dyeriana. Their structures were elucidated by spectroscopic methods and chemical evidence. Compound 1 possessed inhibitory activity against human leukaemia K562 cells with an IC50 value of 39 μmol/L.A new sesquilignan, 7＇,8＇-didehydroherpetotriol （1）, and a new lignan glycoside, （＋）-isolariciresinol-9＇-O-α-L-rhamnopyra- nosy1-（1→6）-[3-D-glucopyranoside （2）, were isolated from the branches of Dipteronia dyeriana. Their structures were elucidated by spectroscopic methods and chemical evidence. Compound 1 possessed inhibitory activity against human leukaemia K562 cells with an IC50 value of 39 μmol/L.

关 键 词：ACERACEAE Dipteronia dyeriana Lignans Didehydroherpetotriol LEUKAEMIA 

分 类 号：R962[医药卫生—药理学]