Glucose,cellobiose,lactose and raffinose used as chiral stationary phases in HPLC  

作　　者：Jian Yu Wang Feng Zhao Mei Zhang Ya Peng Li Ming Yuan 

机构地区：[1]Department of Chemistry, Yunnan Normal University, Kunming 650092, China

出　　处：《Chinese Chemical Letters》2008年第10期1248-1251,共4页中国化学快报（英文版）

基　　金：National Natural Science Foundation and Yunnan Province's Natural Science Foundation of China(No.20775066No.2005E0006Z).

摘　　要：This paper presents the enantioseparation using glucose, cellobiose, lactose and raffinose as chiral selector bonded to silica gel via an arm in HPLC. Surprisingly, they also possess high enantioseparation selectivity, may be used in normal-phase and reversed- phase mode, and there is a big chiral discriminating complementary. This work indicates that oligosaccharides could soon become very attractive as a new class of chiral stationary phase for HPLC.This paper presents the enantioseparation using glucose, cellobiose, lactose and raffinose as chiral selector bonded to silica gel via an arm in HPLC. Surprisingly, they also possess high enantioseparation selectivity, may be used in normal-phase and reversed- phase mode, and there is a big chiral discriminating complementary. This work indicates that oligosaccharides could soon become very attractive as a new class of chiral stationary phase for HPLC.

关 键 词：OLIGOSACCHARIDES Chiral stationary phase HPLC 

分 类 号：Q5[生物学—生物化学]