东莞市2005～2007年预防接种异常反应监测系统运行效果评价  

Evaluation of immunization-induced adverse reaction monitoring system in Dongguan City.

作　　者：王东[1] 毛东波[1] 夏宪照[1] 杨庆东 侯达繁 朱建琼[1] 王莹[1] 袁焕章[1] 莫想换[1] 

机构地区：[1]东莞市疾病预防控制中心,广东东莞523006 [2]东莞市横沥医院,广东东莞523460 [3]东莞市清溪医院,广东东莞523600

出　　处：《中国热带医学》2008年第11期1999-2001,共3页China Tropical Medicine

摘　　要：目的了解东莞市各种疫苗预防接种异常反应的发生情况,评价东莞市疑似预防接种异常反应(AEFI)监测和处理控制系统的运行状况,方法对该系统2005～2007年所收集的AEFI病例进行描述性分析。结果全市共报告AEFI 569例,其中一般反应272例(47.80%),异常反应267例(46.92%),偶合症18例(3.16%),不明原因7例(1.23%),心因性反应4例(0.70%),实施差错事故1例(0.18%)。男性报告数多于女性。在所使用的24种疫苗中有20种出现不良反应,报告平均发生率为4.19/10万,以肺炎疫苗、HIB和百白破的发生率最高,且百白破的报告数最多。在报告的预防接种不良反应中,最常见的为过敏性皮疹、发热和局部红肿浸润反应。结论该系统在评价疫苗的安全性,发现AEFI发生的危险因素,改善预防接种服务质量起着重要作用。Objective To understand the occurrence of adverse events following immunization （AEFI） in Dongguan and evaluate the running status of the monitoring control system for AEFI. Methods AEFI data from 2005 to 2007 were analyzed. Results There 569 AEFI case were reported including 272 cases with general reaction （47.80%）, 267 cases with abnormal reaction （46.92%）, 18 cases with coincidental reaction （3.16%） , 7 cases with unknown reason （1.23%） , 4 cases with injection reaction （0.70%） and a programme error （0. 18% ）. There male cases were more than that of female ones. Adverse reactions were induced by 20 vaccines out of the 24 kinds of vaccines used, especially the pneumococal vaccine , HIB and the DPT. The most commonly reported adverse events were rash, fever and local reaction. Conclusion The system palys a key role in evaluaton of the safety of immunization, detection of AEFI and improvement of vaccination quality.

关 键 词：预防接种 异常反应 监测 评价 

分 类 号：R186[医药卫生—流行病学]