葡萄球菌医院感染耐药性分析  

Analysis on drug resistance of Staphylococci in hospital infection

作　　者：龙显科[1] 汤丽霞[1] 覃志坚[1] 唐任光[1] 

机构地区：[1]右江民族医学院附属医院检验科,广西百色533000

出　　处：《检验医学与临床》2008年第21期1297-1298,共2页Laboratory Medicine and Clinic

摘　　要：目的了解葡萄球菌的致病性及耐药现状,为控制医院感染提供参考。方法对从医院感染患者标本中分离出的195株葡萄球菌进行详细鉴定,并进行耐甲氧西林金黄色葡萄球菌(MRSA)检测及结合临床相关资料进行分析。结果195株葡萄球菌中金黄色葡萄球菌56株(28.72%),表皮葡萄球菌37株(18.97%),施氏葡萄球菌31株(15.89%)。检出MRSA11株(19.42%),耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)18株(12.94%)。凝固酶阴性葡萄球菌(CNS)对青霉素敏感率很低(0.0%),MRSA对阿奇霉素、安美汀的耐药性达68.9%和85.2%,而MRCNS对头孢唑林、阿奇霉素的耐药性达57.6%和70.6%。结论及时了解葡萄球菌感染的变化及耐药性变迁,能为葡萄球菌感染的治疗提供依据。Objective To study the pathogenicity and drug resistance status of Sphylococcus so as to offer related information to the control of hospital infection. Methods Careful identification and meticillin resistant Staphylococci（MRS） test were made to all 195 strains of staphylococci isolated from clinical specimens,and then the results and related clinical data were analyzed. Results Of all the 195 strains of staphylococci,56 strains（28. 72%） were staphylococcus aureus, 37 （18. 97%） were staphylococcus epidermidis, 31 （15.89%） were s. sch leiferi. Among the samples 11 （19.42 % ） were methicitlin resistant staphylococcus aureus （MRSA） and 18 （12.94 % ） were meticillin-resistant eoagulase-negative staphylococcus（MRCNS） by MRS test. The sensitive rate of coagulase-negative staphylococeus（CNS） to penicillin was very low（0.0%）, the drug resistance rate of MRSA to amoxicillin and azithromyein achieved to 68.9 G- 85.2%, while MRCNS to cefazolin and azithromyein achieved to 57.6 %- 70.6 %. Conclusion To understand the diversification of staphylococcus infection and variation of drug resistance promptly is necessary to get evidence for the prevention and treatment of hospital acquired staphylococcus infection.

关 键 词：葡萄球菌属 交叉感染 药物耐受性 

分 类 号：R378.11[医药卫生—病原生物学] R969.4[医药卫生—基础医学]