肾小球肾炎患者血和尿液Sc5b-9的检测及影响因素  

Measurement of Sc5b-9 Urine in Patients with Glomerulonephritis and Influenced Factors

作　　者：孙敏[1] 

机构地区：[1]北华大学医学检验学院

出　　处：《北华大学学报（自然科学版）》2008年第5期428-430,共3页Journal of Beihua University（Natural Science）

基　　金：吉林市科技局科研基金项目(2003011)

摘　　要：目的探讨肾小球肾炎患者血液和尿中Sc5b-9的变化规律及测定影响因素．方法采用ELISA法检测血液及尿中的Sc5b-9蛋白水平．结果肾小球肾炎患者尿的pH、红细胞及白细胞不影响Sc5b-9水平，但将尿液置-70℃冷冻后可使Sc5b-9水平提高．结论肾小球肾炎患者尿中Sc5b-9来源于肾脏，其含量变化可反映肾脏的损害程度；血与尿中Sc5b-9水平无相关性．将尿液置-70℃冷冻后可影响ScSb-9水平．Objective To discuss the changing regularity of Sc5b-9 in plasma and urine of the patients with glomerulonephritis and influenced factors. Methods To inspect Sc5b-9 protein level in plasma and urine treated with ELISA. Results pH,leukocyte and erythrocyte Sc5b-9 in urine of the patients with glomerulonephritis did not influence Sc5b-9 level. However freezing urine at - 70 ~C can raise Sc5b-9 level. Conclusion The urinary Sc5b-9 of patients with glomerulonephritis is from renal. The level of urinary Sc5b-9 may contribute to the pathogenesis glomerular injury in disease. There is no correlation between plasma Sc5b-9 level and urinary Sc5b-9 level. Freezing urine at - 70℃ can influence Sc5b-9 level.

关 键 词：末端补体复合物 肾小球肾炎 SC5B-9 

分 类 号：R692.3[医药卫生—泌尿科学]