高血压患者胰岛素抵抗机制的临床探讨  

CLINICAL DISCUSSION OF INSULIN RESISTANCE MECHANISM ON PRIMARY HYPERTENSION

作　　者：马建国[1] 徐自理[1] 侯子山[1] 

机构地区：[1]临沂市人民医院心内科

出　　处：《临沂医学专科学校学报》1997年第3期179-181,共3页Journal of Linyi Medical College

摘　　要：目的：探讨高血压患者胰岛素抵抗机制。方法：检测32例高血压病并胰岛素抵抗患者，16例继发性高血压患者及22例正常血压者葡萄糖耐量试验前后血糖及血浆胰岛素的变化。结果：高血压病患者的血糖及血浆胰岛素水平均高于继发性高血压患者及正常血压者，有显著性差异。继发性高血压患者与正常人之间无显著性差异。结论：胰岛素抵抗可能为高血压病发病机制之一，而不是血压升高的结果。Aim:To explore the mechanism of insulin resistance of patients with primary hypertension. Methods: The plasma levels of glucose and insulin were measured andanalysed before and after glucose load in 32 patients of essential or primary hypertensives with insulin resistance , 18 patients of secondary hypertensives and 22 health persons. Results: The plsma levels of glucose and insulin in essential hypertensives were apparently higher than those of secondary hypertensives and mormotonsives. And therewas signficant differcence (P< 0. 01) between essential hypertensives and control cases.Conclusions: Insulin resistance may be one of the primary pathogenic factors in essentialhypertension, but not be a secondary factor.

关 键 词：高血压 胰岛素抵抗 糖耐量试验 

分 类 号：R544.1[医药卫生—心血管疾病]