乙型肝炎病毒感染者PreS1-Ag、PreS2-Ag与HBV测定分析  

The PreS1-Ag,PreS2-Ag and HBV determination and analysis of hepatitis B virus infected person

作　　者：金明林[1] 黎明新[2] 

机构地区：[1]沈阳医学院生物化学教研室,辽宁沈阳110034 [2]沈阳医学院奉天医院检验科,辽宁沈阳110024

出　　处：《中国医药导报》2008年第31期77-78,共2页China Medical Herald

摘　　要：目的:研究乙型肝炎病毒(HBV)感染者PreS1-Ag和PreS2-Ag与HBV-M之间的关系。方法:用ELISA法对316例HBV感染者血清进行PreS1-Ag和PreS2-Ag及HBV-M检测。结果:对照组的血清PreS1-Ag和PreS2-Ag与HBV-M为阴性,而HBV感染者血清PreS1-Ag和PreS2-Ag在三种主要模式中的检出率分别为88.8%,76.3%;70.3%,55.4%;68.2%,55.7%。结论:PreS1-Ag和PreS2-Ag更敏感地反映了HBV的感染和复制程度,对乙肝血清标志物检测起重要的补充作用。Objective： To study the correlation of PreS1-Ag,PreS2-Ag and HBV-M in hepatitis B virus （HBV） infected person. Methods： ELISA method was used in the detection PreS1-Ag,PreS2-Ag and HBV-M in serum of 316 cases of HBV-infected people. Results： The control group serum PreS1-Ag,PreS2-Ag and HBV-M was negative, but HBV infected group PreS1-Ag,PreS2-Ag and HBV-M detection rates in three models were 88.8%,76.3%; 70.3%,55.4%; 68.2%, 55.7%. Conclusion： PreS1-Ag and PreS2-Ag were more sensitive to HBV infection and replication level and play an important supplementary role in HBV serum markers detection.

关 键 词：乙型肝炎病毒 PreS1-A PreS2-Ag 

分 类 号：R446.6[医药卫生—诊断学]