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机构地区:[1]东南大学生物电子学国家重点实验室,江苏省生物材料与器件重点实验室,江苏南京210096
出 处:《中国激光》2008年第11期1821-1824,共4页Chinese Journal of Lasers
基 金:国家自然科学基金重点项目(90406023);中国博士后基金(20060400904);江苏省博士后科研计划(0601013B)资助课题
摘 要:为了方便、快速、低成本地检测样品,提出一种内嵌光纤型微流控芯片的制备方法。利用248 nm的KrF准分子激光在聚甲基丙烯酸甲酯(PMMA)基片上进行微加工,构建芯片结构,并嵌入腐蚀过的直径35μm的单模光纤,从而形成内嵌光纤型芯片。探讨了准分子激光加工参数以及嵌入光纤的方法。结果表明,用准分子激光加工芯片,可控性好、简便可靠、加工过程可实现无人化。内嵌光纤实现了光纤的相互对准以及光纤对流道中央的对准,可以灵敏地获取样品的光学信号。In order to detect samples with convenience, high speed and low cost, we presented a fabrication method of microchip with embedded optical fibers. Polymethyl methacrylate (PMMA) microchip with embedded optical fibers of 35 μm diameter was fabricated using a 248 nm KrF excimer laser processing technique. The processing parameters of excimer laser and the embedding method of optical fibers were studied. The results show that the excimer laser processing is controllable, easy, reliable to realize automation. With the embedded optical fiber system, the mutual aim of the fibers and the aim between the fibers and channel core can be realized, thus resulting in the sensitive detection of optical signal, which is expected to have good applications in the portable blood cell counts and bio-sensors.
关 键 词:激光技术 准分子激光微加工 微流控芯片 光纤 聚甲基丙烯酸甲酯
分 类 号:TG665[金属学及工艺—金属切削加工及机床]
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