皮下胰岛素抵抗的研究进展  

Subcutaneous insulin resistance: a new type of insulin resistance

作　　者：赵明[1] 刘志民[1] 

机构地区：[1]南京军区南京总医院内分泌科,江苏南京210002

出　　处：《医学研究生学报》2008年第10期1095-1097,共3页Journal of Medical Postgraduates

基　　金：江苏省自然科学基金资助项目(批准号:BK20007574)

摘　　要：皮下胰岛素抵抗是葡萄糖代谢对胰岛素皮下注射不敏感,但对静脉注射敏感,其机制主要是皮肤阻碍或延迟胰岛素吸收进入循环。皮下胰岛素抵抗的治疗包括使用抑肽酶、抗凝剂、肌内注射胰岛素等。文中就皮下胰岛素抵抗的研究进展进行综述。Subcutaneous insulin resistance is a condition in which glucose is insensitive to insulin from the subcutaneous tissue,but sensitive to that by intravenous injection.The mechanism of subcutaneous insulin resistance is mainly associated with skin obstruction or delayed entry of insulin into blood circulation.The treatment of the problem involves Aprotinin,anticoagulant and intramuscular injection of insulin.This paper offers an overview of the advances in the researches of subcutaneous insulin resistance.

关 键 词：皮下胰岛素抵抗 吸收 降解 脆性糖尿病 

分 类 号：R335[医药卫生—人体生理学]