水热合成微孔纳米羟基磷灰石  

Synthesis of Microporous Hydroxyapatite via a Hydrothermal Process

作　　者：徐惠[1] 张斯凡[1] 刘小育[1] 苟国俊[1] 

机构地区：[1]兰州理工大学石油化工学院,兰州730050

出　　处：《应用化学》2008年第11期1255-1258,共4页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金(50602020);甘肃省自然科学基金(2007GS05348)资助项目

摘　　要：以Ca（NO3）2.4H2O、P2O5为原料,水-乙醇为溶剂,在碱性介质中,采用水热法合成微孔纳米羟基磷灰石晶体（HAP）,研究了水-乙醇的体积比对产物组成、晶体结构的影响。利用X射线衍射（XRD）、红外光谱（FTIR）、热分析（TG/DTA）、透射电镜（TEM）等检测技术对HAP的晶相、化学组成和形貌进行了表征和分析。结果表明,当V（水）∶V（乙醇）=1∶1时,可得到晶体发育完整、晶体表面孔洞分布均匀（孔密度约为3×10^9个/cm2）和孔径约为1~2 nm的六方柱状纳米羟基磷灰石晶体（60 nm×100 nm）。Microporous hydroxyapatite crystals were synthesized from calcium nitrate and phosphorus oxide in water/ethanol solution by hydrothermal method, and the influence of water-ethanol ratio on the crystal morphology and microstructure was explored. The composition and microstructure of the grown crystals were analyzed by XRD, FTIR, DTA/TGA, and TEM. The results show that perfect hydroxyapatite crystals with hexagonal-dipyramidal phase（60× 100 nm） and micropores were obtained in V（water） ： V（ethanol） = 1 ： 1, and the hole density was about 3 ×10^9/cm2. The presence of micropores（ 1 -2 nm） in the crystal planes might be important for biomedical applications as they could enhance the adhesion between the natural and synthesized bone apatite.

关 键 词：微孔 羟基磷灰石 水热合成 晶体 

分 类 号：O6[理学—化学] TB321[一般工业技术—材料科学与工程]