介入栓塞治疗甲状腺机能亢进实验和临床观察  

A new method for treating thyroidism with interventional embolism

作　　者：张新国[1] 华益慰[1] 李京雨 赵振琴 

机构地区：[1]武警总医院 [2]北京军区总医院外一科

出　　处：《武警医学》1997年第1期13-15,共3页Medical Journal of the Chinese People's Armed Police Force

摘　　要：以１２只犬的２４侧甲状腺前动脉为靶血管，比较使用不同的栓塞剂后的反应，结果提示：褐藻胶微球（ＡＭＧ）较其它栓塞剂的栓塞效果明显且安全便利。２３例原发性甲状腺机能亢进病人以经股动脉插管介入栓塞的方法向甲状腺动脉内注入ＡＭＧ，术后甲亢症状迅速缓解，Ｔ３，Ｔ４可降至正常。随访３ａ，有３例甲亢症状复发，其余２０例治愈。为临床提供了一种甲亢治疗和术前准备的新方法。Various embolic agents were injected separately into anterior thyroid arteries of 12 dogs to compare the embolitic effect.After two weeks,the results of the histology of thyroids,serum T 3,T 4 and plasma calcium suggested that the alginate microglobe(AMG) is superior to sodium morrhuate,iophendylate,iodized oil and spongy gelatin absorbent in embolic effect,safety and expediency.On this basis,AMG was injected into thyriod arteries of 23 patients with primary thyroidism by the interventional embolic technique.After this treatment the symptoms of thyroidism in the patients disappeared quickly,and the levels of T 3,T 4 decreased to normal.The patients were followed up for three years,of whom 20 were recovered,and three had recurrence and received thyroidectomy.The interventional embolism provides a new method for treatment of thyroidism and preparation for operation in clinic.

关 键 词：甲状腺机能亢进 介入治疗 甲状腺动脉 实验 

分 类 号：R581.105[医药卫生—内分泌]