米非司酮、甲氨蝶呤联合应用治疗输卵管妊娠疗效观察  

Curative effect of Mifepristone combining with Methotrexate on tubal pregnancy

作　　者：席艳妮[1] 屈振吉 

机构地区：[1]榆林市第二医院妇产科,陕西榆林719000

出　　处：《延安大学学报（医学科学版）》2008年第3期94-95,共2页Journal of Yan'an University:Medical Science Edition

摘　　要：目的探讨米非司酮联合甲氨蝶呤(MTX)治疗输卵管妊娠的效果,并与单用甲氨蝶呤(MTX)比较,验证米非司酮在输卵管妊娠治疗中的作用。方法将输卵管妊娠患者80例随机分成两组,分别接受单用MTX、米非司酮联合MTX治疗,记录症状消失、尿HCG转阴、血hCG明显下降、包块缩小及达治愈标准的时间。结果米非司酮联合MTX组与MTX组比较,上述指标差异均有显著性意义,(P<0.05或P<0.01)。两组治疗β-hCG在1000～2000IU/L,两组疗效有显著差异,(P<0.05)。结论米非司酮联合MTX治疗输卵管妊娠效果优于单纯应用MTX。Objective： To investigate the curative effect of Mifepristone with methotrexate （MTX） in treating tubal pregnancy. Methods 80 women who have been diagnosed having tubal pregnancy were divided into two groups. Group 1 was treated with MTX only and Group 2 treated with Mifepristone and MTX. The time for symptom disappear, urine - hCG turning into negative, an obvious descent of hCC, lump diminution and reaching cure standard was recorded. Results There were significant differences in therapeutic results exhibited by above parameters between the two groups （P 〈 0.05 or P 〈 0.01 ）. Conclusion Mifepristone combining with MTX is proved superior over single MTX in treating tubal pregnancy.

关 键 词：米非司酮 甲氨蝶呤 输卵管妊娠 疗效 

分 类 号：R714.21[医药卫生—妇产科学]