我院2004～2007年抗菌药物的使用与铜绿假单胞菌耐药水平变化的关系  

Consumption of Antibiotics from 2004 to 2007 and Variation of Drug Resistance Level of Pseudomonas Aeruginosa

作　　者：王国俊[1] 张青碧[2] 曾秘[1] 马兰[3] 

机构地区：[1]泸州医学院附属医院药剂科,泸州市646000 [2]泸州医学院公共卫生系,泸州市646000 [3]泸州医学院药学院,泸州市646000

出　　处：《中国药房》2008年第32期2513-2516,共4页China Pharmacy

摘　　要：目的:为临床合理应用抗菌药物提供科学依据。方法:统计我院2004～2007年住院患者抗菌药物使用情况以及铜绿假单胞菌的药敏试验结果,数据用SPSS13.0统计软件进行多元线性回归,分析我院铜绿假单胞菌耐药水平与抗菌药物用量的关系。结果:耐药性铜绿假单胞菌的增多与抗菌药物的消耗量之间存在一定的量化关系。结论:治疗铜绿假单胞菌感染,临床应尽可能根据药敏试验结果用药。OBJECTIVE： To analyze the relationship between the drug - resistance level of pseudomonas aeruginosa and the consumption of antibiotics so as to provide scientific basis for the rational use of antibiotics. METHODS： The consumption of antibiotics in inpatients in our hospital from 2004 to 2007 and the susceptibility test results on pseudomonas aeruginosa were investigated and the data were subjected to multiple linear regression using SPSS13.0 software. RESULTS： Positive association was noted between drug resistance of pseudomonas aeruginosa and the consumption of antibiotics. CONCLUSION： Antibiotics should be used rationally in accordance with clinical sensitivity test results in the treatment of infection caused by pseudomonas aeruginosa and the abuse of antibiotics should be reduced so as to reduce the production of drug- resistance bacteria.

关 键 词：铜绿假单胞菌 抗菌药物 耐药水平 用药频度 

分 类 号：R969.3[医药卫生—药理学] R95[医药卫生—药学]