缺铁性贫血患者的畸变产物耳声发射研究  

Changes of distortion product otoacoustic emissions in the patients with iron deficient anaemia

作　　者：沈锋[1] 孙爱华[2] 叶青 毕婕[3] 陈珏[3] 张婷[3] 陈珍辛[3] 方桢[3] 

机构地区：[1]上海市静安区中心医院耳鼻咽喉科,上海200040 [2]第二军医大学长征医院耳鼻咽喉科 [3]上海市闸北区中心医院耳鼻咽喉科

出　　处：《临床耳鼻咽喉头颈外科杂志》2008年第19期883-885,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：国家自然科学基金(No:30472124);上海市闸北区科学技术委员会基金(No:2004闸北青年04)

摘　　要：目的:观察缺铁性贫血患者畸变产物耳声发射(DPOAE)的变化。方法:体检人群按血红蛋白及血清铁蛋白检查结果分组,正常对照组30例60耳,缺铁性贫血患者组30例60耳,分别行DPOAE检查,以4 kHz频率点为观察点。结果:缺铁性贫血患者的DPOAE幅值在4 kHz频率点较正常对照组下降,两者差异有统计学意义(P<0.05)。结论:缺铁性贫血患者DPOAE幅值下降,可导致感音神经性聋。Objective：To observe the changes of distortion product otoacoustic emissions（DPOAE） in the patients with iron deficient anaemia（IDA）.Method：Sixty cases who were taken health physical examination at ZhaBei District Central Hospital were divided into two groups,the normal group（30 cases,60 ears） and the IDA group（30 patients,60 ears） depend on the results of examination of hemoglobin and serum ferritin.The changes of DPOAEs at 4 kHz were observed.Result：A statistically significant decrease of DPOAE threshold level compared with the normal controls was seen at 4 kHz in the patients with IDA.Conclusion：The decreased threshold level of DPOAE at 4 kHz in IDA patients should relate to sensorineural hearing loss directly.

关 键 词：缺铁性贫血 畸变产物耳声发射 

分 类 号：R556.3[医药卫生—血液循环系统疾病]