支气管肺蠊缨滴虫感染的治疗——1例报告及文献复习  

The treatment of bronchopulmonary lophomonas blattarum infection:one case report and literature review

作　　者：姚国忠[1] 曾力强[1] 张波[1] 迟维维[1] 常正山[2] 

机构地区：[1]武警上海总队医院呼吸内科,201103 [2]上海市中国疾病预防控制中心寄生虫病预防控制所,200025

出　　处：《临床肺科杂志》2008年第12期1554-1556,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的分析目前支气管肺蠊缨滴虫感染的现状,进一步提高认识。方法报道1例长期随访病例的治疗情况,结合文献报道的16例,分析在治疗过程中的经验和不足。结果17例中,有12例报道用甲硝唑治疗临床观察提示有效,但有2例长期随访的病例提示甲硝唑类药物及其他抗原虫药物治疗无效。4例有支气管哮喘发作应用肾上腺皮质激素治疗能缓解症状。经支气管镜治疗可以作为辅助治疗方法。结论虽然甲硝唑治疗支气管蠊缨滴虫感染的药理作用机制不明,长期观察也有无效病例,但首次治疗仍应作为首选药物。肾上腺皮质激素能减轻变态反应,可适量使用。Objective To improve the cognition about the treatment of bronchopulmonary lophomonas blattarum infection. Methods One case with treatment over a long period of time was reported, and the treatment experiences or deficienay of 16 cases that were reported earlier in literature were analyzed. Results Of 17 cases, 12 cases were treated with metronidazole, and their clinical symptoms im- proved or disappeared. But 2 cases showed inefficacy, who were either treated with metronidazole or treated with others antiprotozoal drug. 4 cases appeared with bronchial asthma, and after being treated with corticosteroid, they were released from the suffering. Bronchoscope treatment was an effective assistant therapy. Conclusion Although the mechanism that bronchopulmonary lophomonas blattarum infection treated with Metronidazole is not well understood, and some cases showed inefficacy,but Metronidazole is still the first choice to treat bronchopulmonary lophomonas blattarum infection. Suitable dosage aorticostemid should be taken to lighten allergic response.

关 键 词：蠊缨滴虫 超鞭毛虫 肺部感染 药物治疗 

分 类 号：R562[医药卫生—呼吸系统]