5,7-二甲基-1,2,4-三唑并[1,5-a]嘧啶-2-羧酸乙酯的合成与表征  

Synthesis and characterization of 5,7-dimethyl-1,2,4-triazolopyrimidine-2-carboxylate

作　　者：龙德清[1] 唐传球[1] 周新[1] 

机构地区：[1]郧阳师范高等专科学校化学系,湖北丹江口442700

出　　处：《应用化工》2008年第10期1161-1162,共2页Applied Chemical Industry

摘　　要：以5-氨基-1H-1,2,4-三唑-3-羧酸为起始原料,经环化和酯化二步反应,合成了标题化合物5,7-二甲基-1,2,4-三唑并[1,5-a]嘧啶-2-羧酸乙酯,其结构经元素分析1、H NMR和MS表征,并对其质谱裂解途径进行了探讨。A new compound 5,7-dimethyl - 1,2,4 -triazolo [ 1, 5-a ] pyrimidine-2-carboxylic acid ethyl ester has been synthesized based on the starting material 5-amino-1H-1 ,2,4-triazole-3-carboxylic acid by two steps：cyclization and esterification. Structure of the compound was confirmed by elemental analysis, MS and ^1H NMR, and fragmentation mechanism of MS spectra was discussed.

关 键 词：1 2 4-三唑并[1 5-a]嘧啶 羧酸乙酯 合成 表征 

分 类 号：O626[理学—有机化学]