Cellyzyme(蘑菇提取物)的美白、祛皱疗效及安全性观察  

The efficacy and safety of celluzyme (extract of mushroom) facial mask

作　　者：徐媛媛[1] 李远宏[1] 吴严[1] 杨雪松 董光晖[3] 耿龙[1] 高兴华[1] 陈洪铎[1] 

机构地区：[1]中国医科大学附属第一医院皮肤科,辽宁沈阳110001 [2]大庆油田总医院集团龙南医院皮肤科 [3]中国医科大学卫生统计学教研室

出　　处：《中国美容医学》2008年第10期1500-1502,共3页Chinese Journal of Aesthetic Medicine

摘　　要：目的:观察含有Celluzyme(蘑菇提取物)的美白换肤面膜的美白、祛皱作用及安全性。方法:招募30名健康受试者,左右侧面部随机分为治疗侧(使用含Celluzyme的面膜)及对照侧(不用面膜)。于使用面膜前、后不同时间点,检测皮肤颜色及角质层含水量,并由医师及受试者各自进行疗效主观评分。结果:治疗侧L差值(皮肤亮度)显著高于对照侧,而*a差值(反应皮肤的红斑情况)、含水量差值则无明显区别。医师及受试者的主观评分均认定面膜可使皮肤美白、毛孔细致、皱纹减少。结论:美白换肤面膜可安全而有效地改善皮肤色泽和质地。Objective To observe the efficay and safety of celluzyme （extract of mushroom） facial mask. on skin color, pore size, and wrinkles. Methods Thirty healthy volunteers were recruited. One side of face was treated with the facial mask twice a week for a consecutive 4 weeks, according to a randomisation table. The other side was spared and observed as the self control. Before and after each procedure, skin color and water content were measured with spectrophotometer （L： skin lightness; a： erythema） and corneometer, individually. The global assessment were performed both by a blinded dermatologist and by all the volunteers. Results The mean change of L value of the treated side was significantly higher than that of the control side. However, the mean ＊a value and water content did not change differently between the two sides. Both the dermatologist and the volunteers assessed that the celluzyme facial mask could whiten the skin, shrink the pore, and reduce the wrinkle, in the slight to moderate extent. Conclusion Celluzyme facial mask could effectively and safely improve skin cotor and texture.

关 键 词：面膜 美白 换肤 化学剥脱 

分 类 号：R758[医药卫生—皮肤病学与性病学]