活血解毒中药对急性冠状动脉综合征血清sCD40L的影响  

The Effect of Therapeutic Method of Blood-activating and Detoxifying of TCM on Serum Level of sCD40L in the Patients with Acute Coronary Syndrome

作　　者：余蓉[1] 何淑娴 叶秀琳[1] 王湘郴[1] 

机构地区：[1]广东省深圳市福田区人民医院,深圳518033

出　　处：《中国中医急症》2008年第11期1500-1501,共2页Journal of Emergency in Traditional Chinese Medicine

基　　金：广东省中医药局资助课题(No.1060150)

摘　　要：目的观察活血解毒中药对急性冠状动脉综合征(ACS)患者血清可溶性CD40(sCD40L)的影响。方法将62例ACS患者随机分为两组,对照组予以常规西药治疗,治疗组在常规西药治疗基础上加服活血解毒汤,均治疗4周;测定两组治疗后血清sCD40L水平的变化。结果两组患者血清sCD40L水平均降低,而治疗组降低更为明显。结论活血解毒中药能明显降低ACS患者血清sCD40L水平,对ACS炎症反应有抗炎作用,有利于动脉粥样硬化斑块的稳定和ACS的防治。Objective： To observe the effect of therapeutic method of blood - activating and detoxifying on serum level of sCD40L in the patients with acute coronary syndrome （ACS）. Methods： Sixty -two patients with ACS were randomized into two groups. 30 cases of control group with routine treatment of Western medicine, 32 cases of treatment group with therapeutic method of blood -activating and detoxifying of Traditional Chinese Medicine（TCM）. Serum Levels of sCD40L in all of the cases were detected by ELISA before treatment and 4 weeks later. Results： After treatment the Serum Level of sCD40L of both groups decreased significantly, but the observed group changed much more obviously than control group. Conclusion： The therapeutic method of blood - activating and detoxifying of TCM can significantly lowers the Serum Level of sCD40L in patients with ACS. Maybe the therapeutic method of TCM has a beneficial effect on stabilization of arterosclerotic plaque and inhibition of inflammatory reaction.

关 键 词：急性冠状动脉综合征 SCD40L 活血解毒中药 

分 类 号：R541.4[医药卫生—心血管疾病]