韩氏穴位神经刺激仪对大鼠佐剂性关节炎的治疗作用  

HAN'S ACUPOINT NERVE STIMULATOR(HANS)FOR THE TREATMENT OF ADJUVANT ARTHRITIS IN RATS

作　　者：张清泉[1] 徐广银[1] 沙宝熙[1] 马红萍[1] 

机构地区：[1]南通医学院生理教研室,南通226001

出　　处：《中国疼痛医学杂志》1997年第1期45-48,共4页Chinese Journal of Pain Medicine

摘　　要：以佐剂性关节炎大鼠作为病理性疼痛的实验动物模型，用韩氏穴位神经刺激仪进行治疗，结果发现：关节炎大民病阈较正常景明显降低，体温及患肢直径也明显增加；但经过一个疗程治疗后，关节炎大民的症状有明显的改善，表现为痛阈显著提高，体温恢复正常和患肢肿胀程度减轻；腹腔注射维生素B6能显著加强治疗的镇痛作用。结果表明：佐剂性关节炎大鼠可作为病理性疼痛的实验动物模型；韩氏穴位神经刺激仪对关节炎大鼠具有良好的治疗作用；维生素民能加强其镇痛作用。Rats with adjuvant arthritis were used as an animal model of pathological pain inthis experiment and pain threshold was examined by recording the latency of heat -tail flickreflex- The results were as follows:The pain threshold decreased significantly , body temperature and the diameter of the ankle joint of hind leg increased remarkably post inoculation After HAN treatment,the pain threshold increased, while body temperature and the joint diameter decreased significantly The analgesic effect of HAN was enhanced by intraperitoneal injection of Vitamin B6. The results suggest that the adjuvant arthritis could be used as agood model for the study of chronic pain, and HANS did show a good therapeutic effect onadjuvant arthritis in rats,which seemed to be improved by the injection of Vitamin B6.

关 键 词：HANS 关节炎 镇痛 电针镇痛 

分 类 号：R684.3[医药卫生—骨科学] R245.97[医药卫生—外科学]