类风湿性关节痛患者的血清新喋呤和可溶性IL-2受体的测定  

SERUM NEOPTERIN AND SOLUBLE INTERLEUKIN-2 RECEPTOR IN RHEUMATOID JOINT PAIN

作　　者：陈健[1] 金忠棋 林洁[2] 周游 

机构地区：[1]浙江医科大学附属二院,杭州310009 [2]浙江医科大学邵氏医院

出　　处：《中国疼痛医学杂志》1997年第4期201-202,共2页Chinese Journal of Pain Medicine

摘　　要：为早期诊断类风湿性关节痛，笔者检测了142例类风湿性关节痛患者和200例献血员（对照组）血清新喋呤和可溶性IL-2受体水平，结果表明：142例类风湿性关节痛患者组的血清新喋呤、可溶性IL－2受体水平分别为26．2±0.94ng／ml和435±22．6u／ml，而对照组仅为5．2±2．2ng／ml和186．6±31．7u／ml，经统计学检验，两者呈非常显著性差异（P＜0．001），提示血清新喋呤、可溶性IL－2受体测定有助于早期鉴别类风湿急性关节痛的诊断。Neopterin (NPT), soluble interleukin-2 receptor (SIL-2R) in serum have been determined by an enzyme linked Immunosorbent Assay (ELISA) in 142 patients,for reseach of a sensible marker in early diagnosis of rheumatoid joint pain (RJP). As a control group, 200 blood donators were also observed. The result showed that NPT and SIL-2R were 26. 16±0.94 ng/ml and 435. 43±0. 59 u/ml respectively in RJP, 5.2±2. 2ng/ml and 186. 6±31. 7u/ml in normal controls (x±S). NPT and SIL-2R were significantly higher in kiP (P < 0. 001). This work comes to conclusion that NPT,SIL-2R may play important roles in acute RJP.

关 键 词：类风湿性关节炎 疼痛 新喋呤 

分 类 号：R593.22[医药卫生—内科学] R441.1[医药卫生—临床医学]