特发性肺间质纤维化的病因病机探讨  

Discussion on etiopathogenisis and pathogenesis of idiopathic pulmonary fibrosis

作　　者：姜良铎[1] 张晓梅[2] 肖培新 

机构地区：[1]北京中医药大学东直门医院,北京100700 [2]北京中医药大学东方医院,北京100078 [3]中国中医药出版社,北京100013

出　　处：《中华中医药杂志》2008年第11期984-986,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：2003-2006年北京科委课题(No.Y0204003041011)

摘　　要：特发性肺间质纤维化根据发病时间、临床症状等分为早中晚三期;根据病情发展分为慢性进展期和急性加重期。反复感受外邪、环境毒邪为发病外因,肺肾亏虚为发病内因,瘀血痰浊为基本病理产物,痰瘀深伏凝结、肺络痹阻为特发性肺间质纤维化发病关键,并探讨了其不同病期的病机演化。Idiopathic pulmonary fibrosis is divided into chronic progression stage and acute exacerbation stage according to progression of disease ;early, middle and late stage according to onset time and clinic symptoms. It is considered that the etiological factors of idiopathic pulmonary fibrosis are repeated suffering of exogenous pathogen, environmental pathogen, deficiency of lung and kidney. The basic pathological products are blood stasis and phlegm turbid, the key point of pathopoiesis is that phlegm and stasis hides deeply and stagnated, the pulmonary collaterals are blocked. In addition, the evolutions of pathogenesis during its different stage are discussed.

关 键 词：特发性肺间质纤维化 病因 病机 病程分期 

分 类 号：R259[医药卫生—中西医结合]