不同检测系统肾功能测定结果对比分析  

A comparative analysis on the renal function results between two kinds of detection systems

作　　者：刘军[1] 李俊立[1] 周燕[1] 肖美芳[1] 

机构地区：[1]华中科技大学同济医学院附属荆州医院医学检验部,湖北荆州434020

出　　处：《检验医学与临床》2008年第22期1364-1365,共2页Laboratory Medicine and Clinic

摘　　要：目的通过对不同检测系统进行方法学对比分析,探讨各系统之间检测肾功能结果是否具有可比性。方法依据美国临床实验室标准化委员会EP9-A文件要求,每天取新鲜血清样本8份,用奥林巴斯AU1000检测系统、贝克曼CX7检测系统测定肾功能常规4项指标,连续测定5d,计算线性方程和相对偏差,并以美国临床实验室修正法规CLIA′88建议的医学决定水平处的系统误差来判定不同检测系统之间的可比性。结果2个检测系统新鲜血清样本测得结果在均值处的配对t检验差异无统计学意义(P>0.05);各检测项目医学决定水平处的系统误差均在允许误差之内。结论2个检测系统测定肾功能结果相关性良好,其系统误差能为临床所接受。Objective To study the comparability of renal function results measured with different kinds of detection systems by means of methodical comparison. Methods Based on the NCCLS EP9-A document, 8 fresh serum specimens per day were collected to assay 4 routine renal function indices by utilizing the Olympus AU1000 and Backman CX7 detection system respectively. The results for consecutive five days were recorded. Linear equation and relative deviations were calculated. It was judged whether the results on different detect systems were compara- ble according to the systematic error at the.medical decision level as CLIA＇88 recommended. Results Analysis of variance showed the paired t-test results of fresh serum specimens had no significant difference between two detection systems（P〉0.05）. The systematic errors of all results at the medical decision level were acceptable. Conclusion The relativity of renal function results between two detection systems is fine, and the systematic errors between the two detection systems are clinically acceptable.

关 键 词：检测系统 肾/生理学 生物化学 医学决定水平 系统误差 

分 类 号：R446.112[医药卫生—诊断学]