DiStinguishing Structure Change of Cells Based on Analysis of Light Scattering Patterns  

作　　者：金永龙 杨芳 王孟 张宇 顾宁 

机构地区：[1]Jiangsu Key Laboratory for Biomaterials and Devices, State Key Laboratory of BioElectronics, Southeast University, Nanjing 210096

出　　处：《Chinese Physics Letters》2008年第11期4013-4015,共3页中国物理快报（英文版）

基　　金：Supported by the National Natural Science Foundation of China under Grant No 90406023.

摘　　要：We develop a new method to distinguish structural change of cells based on light scattering and Fourier spectra analysis. The light scattering detection system is composed of a laser source, an optical microscope, a CCD with high resolution and low distortion. After the scattering patterns of cells are recorded by the CCD, the Fourier spectra are obtained by the intensity distribution of scattered light. In the experiment, the change of cell structure is designed by sonication treatment. It is found that different typical peaks can be shown in the Fourier spectra of MCF7 cells with and without sonication treatment, which indicates that this method can be used to distinguish the structural change of cells.We develop a new method to distinguish structural change of cells based on light scattering and Fourier spectra analysis. The light scattering detection system is composed of a laser source, an optical microscope, a CCD with high resolution and low distortion. After the scattering patterns of cells are recorded by the CCD, the Fourier spectra are obtained by the intensity distribution of scattered light. In the experiment, the change of cell structure is designed by sonication treatment. It is found that different typical peaks can be shown in the Fourier spectra of MCF7 cells with and without sonication treatment, which indicates that this method can be used to distinguish the structural change of cells.

关 键 词：the power-law exponents PRECIPITATION durative abrupt precipitation change 

分 类 号：O439[机械工程—光学工程]