溶剂法合成2-羟基-1-萘甲酸的工艺研究  

Study on Synthesis Process of 2-hydroxy-1-naphthoic Acid by Solvent

作　　者：沈玉堂[1] 漆琳[1] 殷恒波[1] 刘于民[1] 姜廷顺[1] 

机构地区：[1]江苏大学化学化工学院,江苏镇江212013

出　　处：《化工中间体》2008年第11期31-33,共3页

摘　　要：以β-萘酚和氢氧化钠为原料,正辛烷为溶剂,合成了2-羟基-1-萘甲酸,纯度达98%以上。通过正交实验研究了反应压力、反应温度和反应时间对收率的影响,确定了最佳的工艺条件:反应压力0.8MPa,反应温度90℃,反应时间8h,该条件下收率达82.83%。2-hydroxy-l-naphthoie acid was prepared from β-naphthol and sodium hydroxide in n-octane, the on the yield of 0.8MPa, reaction purity was up to 98%. The effects of the reaction pressure, temperature and time the product by orthogonal test. Under the optimum technology： reaction pressure temperature 90 ℃ and reaction time 8 h, the yield of the product was 82.83%.

关 键 词：2-羟基-1-萘甲酸 Kolbe-Schmitt反应 溶剂法 正交实验 

分 类 号：TQ245.4[化学工程—有机化工]